Members

Lun Yao    Associate Professor

Education and Working Experience

2004-2008 Lanzhou University  Bachelor

2008-2013 University of Chinese Academy of Sciences (UCAS)  Doctor

2014-2019 KTH Royal Institute of Technology  Postdoctor

2021-Now DICP CAS Associate Professor

Research Interest

Metabolic engineering of methylotrophic bacteria to produce high-value chemicals

Tel: 0411-88133490  Email: yaolun@dicp.ac.cn

Featured Publications

1. Yao L.#, Shabestary K.#, Björk S. M., Asplund-S. J., Joensson H. N., Jahn M., Hudson E. P.*, Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes, Nat. Commun., 2020, 11(1):1666.

2. Yao L., Cengic I., Anfelt J., Hudson E. P.*, Multiple Gene Repression in Cyanobacteria Using CRISPRi, ACS Synth. Biol., 2016, 5, 207-212.

3. Tan X. M.#, Yao L.#, Gao Q. Q., Wang W. H., Qi F. X., Lu X. F.*, Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria, Metab. Eng., 2011, 13, 169-176.

4. Yao L.#, Qi F. X.#, Tan X. M., Lu X. F.*, Improved production of fatty alcohols in cyanobacteria by metabolic engineering, Biotechnol. Biofuels, 2014, 7:94.

5. Kaczmarzyk D.#, Cengic I.#, Yao L., Hudson E. P.*, Diversion of the long-chain acyl-ACP pool in Synechocystis to fatty alcohols through CRISPRi repression of the essential phosphate acyltransferase PlsX, Metab. Eng., 2017, 45, 59-66.

6. Wu W., Zhang L., Yao L., Lu X. F.*, Genetically assembled fluorescent biosensor for in situ detection of bio-synthesized alkanes, Sci. Rep., 2015, 5:10907.

7. Qi F. X., Yao L., Tan X. M., Lu X. F.*, Construction, characterization and application of molecular tools for metabolic engineering of Synechocystis sp. PCC6803, Biotechnol. Lett., 2013, 35, 1655-1661.

8. Shabestary K., Anfelt J., Ljungqvist E., Jahn M., Yao L., Hudson E. P.*, Targeted Repression of Essential Genes To Arrest Growth and Increase Carbon Partitioning and Biofuel Titers in Cyanobacteria. ACS Synth. Biol., 2018, 7, 7, 1669-1675.

9. Liu A. Q., Tan X. M., Yao L., Lu X. F.*, Fatty alcohol production in engineered E. coli expressing Marinobacter fatty acyl-CoA reductases. Appl. Microbiol. Biotechnol., 2013, 97, 7061-7071.