Lun Yao    Associate Professor

Education and Working Experience

2004-2008 Lanzhou University  Bachelor

2008-2013 University of Chinese Academy of Sciences (UCAS)  Doctor

2014-2019 KTH Royal Institute of Technology  Postdoctor

2021-Now DICP CAS Associate Professor

Research Interest

Synthetic biology and metabolic engineering of methlotrophic yeast

Tel: 0411-88133490  Email:

Featured Publications

1. Qiao S.J., Bai F., Cai P., Zhou Y.J., Yao L.*, An improved CRISPRi system in Pichia pastoris, Synth. Syst. Biotechnol., 2023, 8, 479-485.

2. Wu X.Y., Cai P., Yao L., Zhou Y.J.*, Genetic tools for metabolic engineering of Pichia pastoris, Eng. Microbiol., 2023, 3, 100094.

3.Yan C.X., Yu W., Yao L., Guo X.Y., Zhou Y.J., Gao J.Q.*, Expanding the promoter toolbox for metabolic engineering of methylotrophic yeasts,Appl. Microbiol. Biotechnol., 2022, 106(9-10):3449-3464.

4. Yao L.#, Shabestary K.#, Björk S.M., Asplund-S.J., Joensson H.N., Jahn M., Hudson E.P.*, Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes, Nat. Commun., 2020, 11(1):1666.

5. Yao L., Cengic I., Anfelt J., Hudson E.P.*, Multiple Gene Repression in Cyanobacteria Using CRISPRi, ACS Synth. Biol., 2016, 5, 207-212.

6. Tan X.M.#, Yao L.#, Gao Q.Q., Wang W.H., Qi F.X., Lu X.F.*, Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria, Metab. Eng., 2011, 13, 169-176.

7. Yao L.#, Qi F.X.#, Tan X.M., Lu X.F.*, Improved production of fatty alcohols in cyanobacteria by metabolic engineering, Biotechnol. Biofuels, 2014, 7:94.

8. Kaczmarzyk D.#, Cengic I.#, Yao L., Hudson E.P.*, Diversion of the long-chain acyl-ACP pool in Synechocystis to fatty alcohols through CRISPRi repression of the essential phosphate acyltransferase PlsX, Metab. Eng., 2017, 45, 59-66.

9. Shabestary K., Anfelt J., Ljungqvist E., Jahn M., Yao L., Hudson E.P.*, Targeted Repression of Essential Genes To Arrest Growth and Increase Carbon Partitioning and Biofuel Titers in Cyanobacteria. ACS Synth. Biol., 2018, 7, 7, 1669-1675.