课题组成员

翟晓鑫 博士研究生

个人简历

2011-2015   大连大学  学士学位

2016-2019   大连大学  硕士学位

2019-2023   大连化学物理研究所1823组  科研助理

2023今     大连化学物理研究所1823组  博士研究生

研究方向酵母细胞工厂的构建以及甲醇生物转化研究

电话0411-88133490

电子邮箱zhaixiaoxin@dicp.ac.cn

代表文章

1. Ludig D.L.#Zhai X.X.#, Rittner A., Gusenda C., Heinz M., Berlage S., Gao N., Jervis A.J., Zhou Y.J.*, Grininger M.*, Engineering metazoan fatty acid synthase to control chain length applied in yeast, Nat. Chem. Biol., 2026, doi.org/10.1038/s41589-025-02105-w.

2. Hou R., Zhai X.X., Zhou Y.J.*, Gao J.Q.*, From toxin to biofuel: engineering microbes for methanol biomanufacturing, Curr. Opin. Biotechnol.,2026, 98, 103442.

3. Ni X., Zhai X.X., Yu W., Ye M., Yang F., Zhou Y.J., Gao J.Q*, Dynamically regulating homologous recombination enables precise genome editing in Ogataea polymorpha, ACS Synth. Biol, 2024,13(9), 2938-2947.

4. Zhai X.X., Gao J.Q., Li Y.X., Grininger M., Zhou Y.J.*,  Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast, Proc. Natl. Acad. Sci. USA, 2023, 120(12), e2220816120.

5. Zhai X.X., Yao L., Zhou Y.J., Construction of microbial chassis for terpenoid discovery, Synth. Syst. Biotechnol., 2022, 7, 1181-1182.

6. Li Y.X., Zhai X.X., Yu W., Feng D., Shah A.A.,  Gao J.Q.*, Zhou Y.J.*, Production of free fatty acids from various carbon sources by Ogataea polymorpha, Bioresour. Bioprocess., 2022, 9, 78.

7. Cai P., Li Y.X., Zhai X.X., Yao L., Ma X.J., Jia L.Y., Zhou Y.J.*, Microbial synthesis of long‑chain α‑alkenes from methanol by engineering Pichia pastoris, Bioresour. Bioprocess., 2022, 9, 58.

8. Yan C.X., Yu W., Zhai X.X.,Yao L., Guo X.Y.*, Gao J.Q.*, Zhou Y.J., Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha, Synth. Syst. Biotechnol., 2022, 7, 498-505.

9. Zhai X.X., Ji L.L., Gao J.Q., Zhou Y.J.*, Characterizing methanol metabolism‑related promoters for metabolic engineering of Ogataea polymorpha, Appl. Microbiol. Biotechnol., 2021, 105, 8761-8769.

10. Yu W., Gao J.Q., Zhai X.X., Zhou Y.J.*, Screening neutral sites for metabolic engineering of methylotrophic yeast Ogataea polymorpha, Synth. Syst. Biotechnol., 2021, 6, 63-68.

11. Gao J.Q., Gao N., Zhai X.X., Zhou Y.J.*, Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha, iScience, 2021, 24(3), 102168.