We recently published a review on methanol based bio-refinery by using microbes. We first summarized the current progresses in methanol production by using chemical and biological process, which may achieve a sustainable and clean approach for methanol supply. Then, we discussed the achievements and challenges in engineering methylotrophs (bacterial and yeast) and non-methylotrophs (model organisms) for producing a variety of chemicals from methanol, which will further expand the substrate resource for bio-refinery and the product portfolio from methanol. (Text and Image by Jiaoqi Gao)

中文版