Recently, our group published a review paper entitled “Microbial production of limonene and its derivatives: Achievements and perspectives”, with the collaboration with Prof. Xiaobing Yang from Northwest A&F University. This paper discussed the recent progresses in engineering microbes for limonene biosynthesis and derivation with the emphasis on enzyme characterization and pathway optimization. In particular, we introduce the current trends in microbial limonene decoration for the biosynthesis of bio-active molecules such as α-terpineol and perillyl alcohol. We also discuss the feasible strategies for relieving limonene toxicity and enhancing the robustness of microbial cell factories. (Text and Image by Yuyao Ren)
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