Xuan Cao
Education Experience
2008-2012 East China University of Science and Technology Bachelor
2012-2017 East China University of Science and Technology Doctor
2017-2022 DICP CAS Postdoctor
Research Interest
Metabolic engineering of Saccharomyces cerevisiae
Featured Publications
1. Yang S., Chen R.B., Cao X., Wang G.D., Zhou Y.J.*, De novo biosynthesis of the hops bioactive flavonoid xanthohumol in yeast, Nat. Commun., 2024, 15, 253.
2. Cao X., Yu W., Chen Y., Yang S., Zhao Z.K., Nielsen J., Luan H.W., Zhou Y.J.*, Engineering yeast for high-level production of diterpenoid sclareol, Metab. Eng., 2023, 75, 19-28.
3. Cao C.Y., Zhang H.Y., Cao X., Kong S.J., Zhu B.W., Lin X.P*., Zhou Y.J.*, Construction and optimization of nonclassical Isoprenoid biosynthetic pathways in yeast peroxisomes for (+)-valencene production, 2023, J. Agric. Food Chem., 2023, 71, 11124-11130.
4. Yu W., Cao X., Gao J. ., Zhou Y.J.*, Overproduction of 3-hydroxypropionate in a super yeast chassis, Bioresource Technol., 2022, 361, 127690.
5. Cao C.Y., Cao X., Yu W., Chen Y.X., Lin X.P., Zhu B.W.*, Zhou Y.J.*, Global metabolic rewiring of yeast enables overproduction of sesquiterpene (+)-valencene, J. Agric. Food Chem., 2022, 70(23), 7180-7187.
6. Wei L.J.#, Cao X.#, Liu, J.J., Kwak S., Jin Y.S., Wang W., Hua Q.*, Increased accumulation of squalene in engineered Yarrowia lipolytica through deletion of PEX10 and URE2. Appl Environ Microbiol., 2021, 87(17), e0048121.
7. Cao X., Yang S., Cao C., Zhou Y.J.*, Harnessing sub-organelle metabolism for biosynthesis of isoprenoids in yeast, Synth. Syst. Biotechnol., 2020, 5, 179-186.
8. Yang S., Cao X., Yu W., Li S., Zhou Y.J.*, Efficient targeted mutation of genomic essential genes in yeast Saccharomyces cerevisiae, Appl. Microbial. Biotechnol., 2020, 104, 3037-3047.
9. Gao Q., Cao X., Huang Y.Y., Yang J.L., Chen J., Wei L.J.*, Hua Q.*, Overproduction of fatty acid ethyl esters by the oleaginous yeast Yarrowia lipolytica through metabolic engineering and process optimization, ACS Synth. Biol., 2018, 7(5), 1371-1380.
10. Cao X.#, Wei L.J.#, Lin J.Y., Hua Q.*, Enhancing linalool production by engineering oleaginous yeast Yarrowia lipolytica, Bioresource Technol., 2017, 245, 1641-1644.
11. Cao X., Lv Y.B., Chen J., Imanaka T., Wei L.J.*, Hua Q.*, Metabolic engineering of oleaginous yeast Yarrowia lipolytica for limonene overproduction, Biotechnol. Biofuels, 2016, 9(1), 214.
Current position
Jinan Microecological Biomedicine Shandong Laboratory
.
