Publications

Article

Book

Patents

2021-

107. Wu X. Y., Ren Y. Y., Chen S. S., Cai P.*, Zhou Y. J., Production of L-lactic acid from methanol by engineered yeast Pichia pastoris. Bioresour. Technol., 2025, 415, 131730.

106. Yang S., Chen R.B., Cao X., Wang G.D., Zhou Y.J.*, De novo biosynthesis of the hops bioactive flavonoid xanthohumol in yeast, Nat. Commun., 2024, 15, 253.

105. Gao L.H.#, Hou R.#, Cai P., Yao L., Wu X.Y., Li Y.X., Zhang L.H.*, Zhou Y.J.*, Engineering Yeast Peroxisomes for α-Bisabolene Production from Sole Methanol with the Aid of Proteomic Analysis, JACS Au, 2024, 2474-2483.

104. Gao L.H., Zhang K., Shen Y.W., Cai P.*, Zhou Y.J.*, Engineering a versatile yeast platform for sesquiterpene production from glucose or methanol, Biotechnol. J., 2024, 19, 2400261.

103. Yu F.*, Zhou Y.J.*, Sustainable production of porphyrins through synthetic biology, Trends Biotechnol., 2024, doi: 10.1016/j.tibtech.2024.09.009.

102. Ni X., Zhai X.X., Yu W., Ye M., Yang F., Zhou Y.J., Gao J.Q*, Dynamically regulating homologous recombination enables precise genome editing in Ogataea polymorpha, ACS Synth. Biol, 2024,13(9), 2938-2947.

101. Li J.J., Gao J.Q., Ye M., Cai P., Yu W., Zhai X.X., Zhou Y.J.*, Engineering yeast for high-level production of β-farnesene from sole methanol, Metab. Eng., 2024, 85, 194-200.

100. Shen Y.W., Cai P., Gao L.H., Wu X.Y., Yao L., Zhou Y.J.*, Engineering high production of fatty alcohols from methanol by constructing coordinated dual biosynthetic pathways, Bioresour. Technol., 2024, 412, 131396.

99. Xie L.F., Yu W., Gao J.Q., Wang H.Y., Zhou Y.J.*, Ogataea polymorpha as a next-generation chassis for industrial biotechnology, Trends Biotechnol., 2024, doi.org/10.1016/j.tibtech.2024.03.007

98. Xie L.F., Gao J.Q., Zhou Y.J.*, Synthetic biology for Taxol biosynthesis and sustainable production, Trends Biotechnol., 2024, 42(6), 674-676.

97. Ye M., Gao J.Q., Li J.J., Yu W., Bai F., Zhou Y.J.*, Promoter engineering enables precise metabolic regulation towards efficient β-elemene production in Ogataea polymorphaSynth. Syst. Biotechnol., 2024, 9, 234-241.

96.Yu W., Gao J.Q., Zhou Y.J.*, Bioconversion of one carbon feedstocks for producing organic acids, Synth. Biol. J., 2024, 5(5), 1169-1188. (Cover story) (in Chinese)

95. Wang Q., Gao J.Q., Zhou Y.J.*, Metabolic engineering for the efficient co-utilization of  glucose and xylose, Chin. J. Biotechnol., 2024, 40(8), 2710-2730.(in Chinese)

94. Cai P., Wu X. Y., Xie L. F., Shen Y. W., Gao L. H., Zhou Y. J.*, Advances in microbial bioconversion of methanol. SCIENTIA SINICA Chimica, 2024, 54(11), 2199-2218.(in Chinese)

93. Gao J.Q.#, Yu W.#, Li Y.X., Jin M.J., Yao L., Zhou Y.J.*, Engineering co-utilization of glucose and xylose for chemical overproduction from lignocellulose, Nat. Chem. Biol., 2023, 19, 1524-1531. (Cover story)

92. Zhai X.X., Gao J.Q., Li Y.X., Grininger M., Zhou Y.J.*,  Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast, Proc. Natl. Acad. Sci. USA, 2023, 120(12), e2220816120.

91. Cao C.Y., Zhang H.Y., Cao X., Kong S.J., Zhu B.W., Lin X.P*., Zhou Y.J.*, Construction and optimization of nonclassical Isoprenoid biosynthetic pathways in yeast peroxisomes for (+)-valencene production, 2023, J. Agric. Food Chem., 2023, 71, 11124-11130.

90. Wu X.Y., Cai P., Yao L., Zhou Y.J.*, Genetic tools for metabolic engineering of Pichia pastoris, Eng. Microbiol., 2023, 3, 100094.

89. Qiao S.J., Bai F., Cai P., Zhou Y.J., Yao L.*, An improved CRISPRi system in Pichia pastoris, Synth. Syst. Biotechnol., 2023, 8, 479-485.

88. Wu X.Y., Cai P., Gao L.H., Li Y.X., Yao L., Zhou Y.J.*,  Efficient bioproduction of 3‑hydroxypropionic acid from methanol by a synthetic yeast cell factory, ACS Sustainable Chem. Eng., 2023, 11, 6445-6453.

87. Ye M., Gao J.Q., Zhou Y.J.*, Global metabolic rewiring of the nonconventional yeast Ogataea polymorpha for biosynthesis of the sesquiterpenoid β-elemene, Metab. Eng., 2023, 76, 225-231.

86. Cao X., Yu W., Chen Y., Yang S., Zhao Z.K., Nielsen J., Luan H.W., Zhou Y.J.*, Engineering yeast for high-level production of diterpenoid sclareol, Metab. Eng., 2023, 75, 19-28.

85. Yu W., Gao J.Q., Yao L., Zhou Y.J.*, Bioconversion of methanol to 3‐hydroxypropionate by engineering Ogataea polymorpha, Chinese J. Catal., 2023, 46, 84-90.

84. Yan C.X., Gao N., Cao X., Yao L., Zhou Y.J., Gao J.Q.*, Auxotrophs compromise cell growth and fatty acid production in Saccharomyces cerevisiae, Biotechnol. J., 2023, 18(4), e2200510.

83. Cao C.Y., Gao J.Q., Zhu B.W., Zhou Y.J.*, Engineering yeast for bio‑production of food ingredients, Syst. Microbiol. Biomanuf., 2023, 3, 2-11.

82. Yao L., Zhou Y.J.*, Progress in microbial utilization of one-carbon feedstocks for biomanufacturing, Chem. Ind. Eng. Prog., 2023, 42(1), 16-29. (in Chinese)

81. Gao J.Q., Li Y.X., Yu W., Zhou Y.J.*, Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol, Nat. Metab., 2022, 4, 932-943.

80. Cai P., Wu X.Y., Deng J., Gao L.H., Shen Y.W., Yao L., Zhou Y.J.*, Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris, Proc. Natl. Acad. Sci. USA, 2022, 119(29), e2201711119.

79. Chen R.B., Gao J.Q., Yu W., Chen X.H., Zhai X.X., Chen Y., Zhang L.*, Zhou Y.J.*, Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast, Nat. Chem. Biol., 2022, 18, 520-529.

78. Gao N.#, Gao J.Q.#, Yu W., Kong S.J., Zhou Y.J.*, Spatial-temporal regulation of fatty alcohol biosynthesis in yeast, Biotechnol. Biofuels Bioprod., 2022, 15, 141.

77. Zhai X.X., Yao L., Zhou Y.J., Construction of microbial chassis for terpenoid discovery, Synth. Syst. Biotechnol., 2022, 7, 1181-1182.

76. Kong S.J., Yu W., Gao N., Zhai X.X., Zhou Y.J.*, Expanding the neutral sites for integrated gene expression in Saccharomyces cerevisiae, FEMS Microbiol. Lett., 2022, 369, 1-5.

75. Zhang K., Duan X.P., Cai P.,Gao L.H., Wu X.Y., Yao L., Zhou Y.J.*, Fusing an exonuclease with Cas9 enhances homologous recombination in Pichia pastoris, Microb. Cell Fact., 2022, 21, 182.

74. Li Y.X., Zhai X.X., Yu W., Feng D., Shah A.A., Gao J.Q.*, Zhou Y.J.*, Production of free fatty acids from various carbon sources by Ogataea polymorpha, Bioresour. Bioprocess., 2022, 9, 78.

73. Yu W., Cao X., Gao J.Q., Zhou Y.J.*, Overproduction of 3-hydroxypropionate in a super yeast chassis, Bioresource Technol., 2022, 361, 127690.

72. Cai P., Li Y.X., Zhai X.X., Yao L., Ma X.J., Jia L.Y., Zhou Y.J.*, Microbial synthesis of long‑chain α‑alkenes from methanol by engineering Pichia pastoris, Bioresour. Bioprocess., 2022, 9, 58. (Featured article)

71. Cao C.Y., Cao X., Yu W., Chen Y.X., Lin X.P., Zhu B.W.*, Zhou Y.J.*, Global metabolic rewiring of yeast enables overproduction of sesquiterpene (+)-valencene, J. Agric. Food Chem., 2022, 70(23), 7180-7187.

70. Yan C.X., Yu W., Yao L., Guo X.Y., Zhou Y.J., Gao J.Q.*, Expanding the promoter toolbox for metabolic engineering of methylotrophic yeasts,Appl. Microbiol. Biotechnol., 2022, 106(9-10), 3449-3464.

69. Yan C.X., Yu W., Zhai X.X., Yao L., Guo X.Y.*, Gao J.Q.*, Zhou Y.J., Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha, Synth. Syst. Biotechnol., 2022, 7, 498-505.

68. Ji D.W., Hu Y.C., Min X.T., Liu H., Zhang W.S., Li Y., Zhou Y.J., Chen Q.A.*, Skeleton-Reorganizing coupling reactions of cycloheptatriene and cycloalkenones with amines, Angew. Chem. Int. Ed. Engl., 2022, e202213074.

67. Hou R., Gao L.H., Liu J.H., Liang Z., Zhou Y.J.*, Zhang L.H.*, Zhang Y.K., Comparative proteomics analysis of Pichia pastoris cultivating in glucose and methanol, Synth. Syst. Biotechnol., 2022, 7, 862-868.

66. Ji L.L., Ma X.J., Gao J.Q.*, Zhou Y.J., Evaluation of promoters from Ogataea polymorpha, Chin. J. Bioprocess Eng., 2022, 20(1), 20-28. (in Chinese)

65. Feng D., Gao J.Q., Gong Z.W.*, Zhou Y.J.*, Production of fatty acids by engineered Ogataea polymorpha, Chin. J. Biotechnol., 2022, 38(2), 760-771. (in Chinese)

64. Cai P.#, Duan X.P.#, Wu X.Y., Gao L.H., Ye M., Zhou Y.J.*, Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia Pastoris, Nucleic Acids Res., 2021, 49(13), 7791-7805.

63. Gao J.Q., Gao N., Zhai X.X., Zhou Y.J.*, Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha, iScience, 2021, 24(3), 102168.

62. Yu W., Gao J.Q., Zhai X.X., Zhou Y.J.*, Screening neutral sites for metabolic engineering of methylotrophic yeast Ogataea polymorpha, Synth. Syst. Biotechnol., 2021, 6, 63-68.

61. Zhai X.X., Ji L.L., Gao J.Q., Zhou Y.J.*, Characterizing methanol metabolism‑related promoters for metabolic engineering of Ogataea polymorpha, Appl. Microbiol. Biotechnol., 2021, 105, 8761-8769.

60. Ye M., Gao J.Q., Zhou Y.J.*, Engineering non-conventional yeast cell factory for the biosynthesis of natural products, Biotechnol. Bull., 2021, 37(8), 12-24. (in Chinese)

59. Gao L.H., Cai P., Zhou Y.J.*, Advances in metabolic engineering of methylotrophic yeast, Chin. J. Biotechnol., 2021, 37(3), 966-979. (in Chinese)