Peng Cai Postdoctor
Education Experience
2007-2011 Nanjing Forestry University Bachelor
2011-2014 Nanjing Forestry University Master
2014-2017 Shanghai Jiaotong University Doctoral candidate
2017-2018 Zhejiang University Research assistant
2018-2022 DICP CAS and Dalian University of Technology Joint Doctor
2022-now DICP CAS Postdoctor
Research Interest
Efficient bioconversion of methanol and development of yeast synthesis biology methods
Tel：0411-88133490 Email：jasoncai@dicp.ac.cn
Featured Publications
1. Wu X. Y., Ren Y. Y., Chen S. S., Cai P.*, Zhou Y. J., Production of L-lactic acid from methanol by engineered yeast Pichia pastoris. Bioresour. Technol., 2025, 415, 131730.
2. Gao L.H.#, Hou R.#, Cai P., Yao L., Wu X.Y., Li Y.X., Zhang L.H.*, Zhou Y.J.*, Engineering Yeast Peroxisomes for α-Bisabolene Production from Sole Methanol with the Aid of Proteomic Analysis, JACS Au, 2024, 2474-2483.
3. Shen Y.W., Cai P., Gao L.H., Wu X.Y., Yao L., Zhou Y.J.*, Engineering high production of fatty alcohols from methanol by constructing coordinated dual biosynthetic pathways, Bioresour. Technol., 2024, 412, 131396.
4. Gao L.H., Zhang K., Shen Y.W., Cai P.*, Zhou Y.J.*, Engineering a versatile yeast platform for sesquiterpene production from glucose or methanol, Biotechnol. J., 2024, 19, 2400261.
5. Cai P., Wu X. Y., Xie L. F., Shen Y. W., Gao L. H., Zhou Y. J.*, Advances in microbial bioconversion of methanol. SCIENTIA SINICA Chimica, 2024, 54(11), 2199-2218.(in Chinese)
6. Wu X.Y., Cai P., Yao L., Zhou Y.J.*, Genetic tools for metabolic engineering of Pichia pastoris, Eng. Microbiol., 2023, 3, 100094.
7. Qiao S.J., Bai F., Cai P., Zhou Y.J., Yao L.*, An improved CRISPRi system in Pichia pastoris, Synth. Syst. Biotechnol., 2023, 8, 479-485.
8. Wu X.Y., Cai P., Gao L.H., Li Y.X., Yao L., Zhou Y.J.*, Efficient bioproduction of 3‑hydroxypropionic acid from methanol by a synthetic yeast cell factory, ACS Sustainable Chem. Eng., 2023, 11, 6445-6453.
9. Cai P., Wu X.Y., Deng J., Gao L.H., Shen Y.W., Yao L., Zhou Y.J.*, Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris, Proc. Natl. Acad. Sci. USA, 2022, 119(29), e2201711119.
10. Cai P., Li Y.X., Zhai X.X., Yao L., Ma X.J., Jia L.Y., Zhou Y.J.*, Microbial synthesis of long‑chain α‑alkenes from methanol by engineering Pichia pastoris, Bioresour. Bioprocess., 2022, 9, 58. (Featured article)
11. Zhang K., Duan X.P., Cai P.，Gao L.H., Wu X.Y., Yao L., Zhou Y.J.*, Fusing an exonuclease with Cas9 enhances homologous recombination in Pichia pastoris, Microb. Cell Fact., 2022, 21, 182.
12. Cai P.#, Duan X.P.#, Wu X.Y., Gao L.H., Ye M., Zhou Y.J.*, Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia Pastoris, Nucleic Acids Res., 2021, 49(13), 7791-7805.
13. Cai P., Gao J.Q., Zhou Y.J.*, CRISPR-mediated genome editing in non-conventional yeasts for biotechnological applications, Microb. Cell Fact., 2019, 18, 63.
