课题组成员

周雍进

课题组长CV

周雍进,博士,研究员,博士生导师,研究组组长。国家自然科学基金委优秀青年基金项目获得者(2019)、国家引进人才青年项目入选者(2018)、中科院引进人才(2017)。曾于江南大学获得食品科学与工程学士学位(2006);天津大学获得生物化工硕士学位(2008);大连化学物理研究所获得生物化工博士学位(2012);2012-2016年在瑞典查尔姆斯理工大学从事博士后研究。2017年1月回到中科院大连化物所组建合成生物学与生物催化课题创新特区研究组,受聘为课题组长。曾在 Cell、Nature Energy、Nature Chemical Biology,Nature Communications、JACS、PNAS 等期刊发表论文50余篇,被引用1800余次。曾获得2015年度中国药学会科学技术奖一等奖,2016年国际代谢科学会议青年科学家奖,2018年‘伦世仪’基金会杰出青年学者奖,2019 年全国生物技术创新大会"最具发展潜力奖"。目前担任 FEMS Yeast Research 等多个学术期刊编委。

代表文章

1. Chen R. B., Yang S., Zhang L., Zhou Y. J.*, Advanced strategies for production of natural products in yeast, iScience, 2020, 23, 100879.

2. Yang S., Cao X., Yu W., Li S., Zhou Y. J.*, Efficient targeted mutation of genomic essential genes in yeast Saccharomyces cerevisiae, Appl. Microbial. Biotechnol., 2020, 104, 3037-3047.

3. Duan X. P., Ma X. J., Li S.Y., Zhou Y. J.*, Free fatty acids promote transformation efficiency of yeast, FEMS Yeast Res., 2019, 19, foz069.

4. Zhou Y. J.*,  Expanding the terpenoid kingdom, Nat. Chem. Biol., 2018, 14, 1069-1070.

5. Yu T.#, Zhou Y. J.#, Huang M. T., Liu Q. L., Pereira R., David F., Nielsen J.*,  Reprogramming yeast metabolism from alcoholic fermentation to lipogenesis, Cell, 2018, 174(6), 1549-1558.

6. Zhou Y. J., Kerkhoven E., Nielsen J.*, Barriers and opportunities in bio-based production of hydrocarbons, Nat. Energy, 2018, 3, 925-935.

7. Zhou Y. J.*, Hu Y., Zhu Z., Siewers V., Nielsen J.*, Engineering 1-alkene biosynthesis and secretion by dynamic regulation in yeast, ACS Syn. Biol., 2018, 7(2), 584-590.

8. Gong Z., Nielsen J.*, Zhou Y. J.*, Engineering robustness of microbial cell factories, Biotechnol. J., 2017, 12(10), 1700014.

9. Zhou Y. J.*, Buijs N. A., Zhu Z., Gómez D. O., Boonsombuti A., Siewers V., Nielsen J.*, Harnessing yeast peroxisomes for biosynthesis of fatty acid-derived biofuels and chemicals with relieved side-pathway competition, J. Am. Chem. Soc., 2016, 138 (47), 15368-15377.

10. Zhou Y. J., Buijs N. A., Zhu Z., Qin J., Siewers V., Nielsen J.*, Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories, Nat. Commun., 2016, 7, 11709.