课题组成员

栾宏伟  副研究员

个人简历

1995-1999  辽宁大学 学士学位

2002-2008  大连化物所 博士学位

2008-2012  大连化物所生物技术部 助理研究员

2012-2017  大连化物所生物技术部1806组 副研究员

2017今    大连化物所生物技术部1823组 副研究员

研究方向:食用菌及功能食品的开发

电话:0411-88133490

电子邮箱:lhw@dicp.ac.cn

代表文章

1. Li Y.X., Yu W., Shan L., Zhai X.X., Yang F., Luan H.W.*, Gao J.Q.*, Zhou Y.J., In vivo multi-enzymatic catalysis for bioproduction of L-lactic acid from sole methanol, Biotechnol. J., 2026, 21(3), e70211.

2. Dou T.Y., Luan H.W., Ge G.B., Dong M.M., Zou H.F., He Y.Q., Cui P., Wang J.Y., Hao D.C., Yang S.L., Yang L.*, Functional and structural properties of a novel cellulosome-like multienzyme complex: efficient glycoside hydrolysis of water-insoluble 7-xylosyl-10-deacetylpaclitaxel, Sci Rep., 2015, 5, 13768.

3. Luan H.W., Dou T.Y., Liu X.B., Li S.Y., Du X.F., Yang L.*, Enzymatic hydrolysis of 7-xylosyltaxanes by an extracellular xylosidase from Cellulosimicrobium cellulans, Biotechnol Lett., 2015, 37, 1905-1910.

4. Zhou K., Luan H.W., Hu Y., Ge G.B., Liu X.B., Ma X.C., Hou J., Wang X.L., Yang L.*,  Isolation and characterization of a novel α-glucosidase with transglycosylation activity from Arthrobacter sp. DL001, J. Mol. Cataly. B-Enzym., 2012, 80, 48-57.

5. Ge G.B., Liang S.C., Liu X.B., Hu Y., Mao Y.X., Zhang Y.Y., Luan H.W., Qiu M.H., Yang L.*, Rapid Qualitative and Quantitative Determination of Seven Valuable Taxanes from Various Taxus Species by UFLC-ESI-MS and UFLC-DAD, Planta Med., 2010, 76(15), 1773-1777.

6. Dong P.P., Ge G.B., Zhang Y.Y., Ai C.Z., Li G.H., Zhu L.L., Luan H.W., Liu X.B., Yang L.*, Quantitative structure-retention relationship studies for taxanes including epimers and isomeric metabolites in ultra fast liquid chromatography, J. Chromatogr. A., 2009, 1216, 7055-7062.

7. Hu Y., Luan H.W., Liu H.X., Ge G.B., Zhou K., Liu Y., Yang L.*, The acceptor specificity and transfer efficiency of a β-glycosidase from the China white jade snail, Biosci. Biotech. Bioch., 2009, 73(3), 671-676.

8. Hu Y., Luan H.W., Ge G.B., Liu H.X., Zhou K., Liu Y., Yang L.*, Deoxynojirimycin enhanced the transglycosylation activity of a glycosidase from the China White Jade Snail, J. Biotechnol., 2009, 139, 229-335.

9. Ge G.B., Luan H.W., Zhang Y.Y., He Y.Q., Liu X.B., Yang L., Wang Z.T., Yang L.*, Profiling of yew hair roots from various species using ultra-performance liquid chromatography-electrospray ionization mass spectrometry, Rapid Commun. Mass Sp., 2008, 22(15), 2315-2323.

10.Hu Y., Luan H.W., Zhou K., Ge G.B., Yang S.L., Yang L.*, Purification and characterization of a novel glycosidase from the China white jade snail (Achatina fulica) showing transglycosylation activity, Enzyme Microb. Tech., 2008, 43 (1), 35-42.

11. Ge G.B., Zhang Y.Y., Hao D.C., Hu Y., Luan H.W., Liu X.B., He Y.Q., Wang Z.T., Yang L.*, Chemotaxonomic Study of Medicinal Taxus Species with Fingerprint and Multivariate Analysis, Planta Med., 2008, 74, 773-779.

12. Hu Y., Luan H.W., Hao D.C., Xiao H.B., Yang S.L., Yang L.*, Purification and characterization of a novel Ginsenoside-hydrolyzing β-D-glucosidase from the China white jade snail (Achatina fulica), Enzyme Microb. Tech., 2007, 40, 1358-1366.

13. Luan H.W., Liu X., Qi X.H., Hu Y., Hao D.C., Cui Y., Yang L.*, Purification and Characterization of a Novel Stable Ginsenoside Rb1-Hydrolyzing β-D-glucosidase from China White Jade Snail, Process Biochem., 2006, 41, 1974-1980.

14. 栾宏伟,胡莹,刘兴宝,郝大程,杨凌, 一种来源于Leifsonia shinshuensis DICP 16菌体的β-D-木糖苷酶的分离纯化及其性质, 生物工程学报,2008, 24(5), 867-873.

15. 刘兴宝,栾宏伟,葛广波,侯琨,杜逊甫,杨凌, 工业色谱法分离制备7-木糖基-10-去乙酰紫杉醇酶解产物10-去乙酰紫杉醇, 色谱2012, 30(2), 165-169.

16. 刘兴宝,栾宏伟,葛广波,闫黎,杨凌, 大孔吸附树脂提取7-木糖-10-去乙酰紫杉醇酶解产物10-去乙酰紫杉醇,天然产物研究与开发2009, 21(3), 496-501.

17. 李洪刚,杨义,何克江,栾宏伟,杨凌, 分组和单体人参皂苷的批量制备,首都医药2004, 11(14), 52-53.

18. 李洪刚,何克江,韩蔚,栾宏伟,杨凌, 树脂联用纯化人参总皂苷,首都医药2004, 11(12), 48-51.

19. 何克江,韩 蔚,栾宏伟,杨凌, 纯化和分光光度法检测联用的人参总皂苷的简易测定方法,药物分析杂志2003, 23(4), 284-288.

专利

1. 栾宏伟, 张辉, 一种从红豆杉属植物中提取紫杉醇及其衍生物的方法,专利号:201310067916.4

2. 杨凌,何克江,杨义,栾宏伟,  用酶水解人参皂甙制备20-β-D-吡喃葡萄糖基原人参二醇,专利号:ZL01133410X

3. 杨凌,周坤,栾宏伟, 一种用于烷基糖苷合成的微生物及其应用,专利号:201110030590.9

4. 杨凌,侯琨,栾宏伟, 一种生产7-木糖-10-去乙酰紫杉醇的方法及其专用培养基,专利号:201210566819.5

5. 杨凌,窦同意,栾宏伟,刘兴宝,侯琨, 一种纤维化纤维微细菌菌株及其应用,申请号:201310245307.3

6. 杨凌,窦同意,栾宏伟,刘兴宝,李世阳, 一种木糖苷酶Xyl_S及其编码基因与应用,申请号:201310251300.2