高教琪 副研究员
个人简历
2008-2012 大连理工大学 学士学位
2012-2017 大连理工大学 博士学位
2015-2016 美国匹兹堡大学 联合培养
2017-2022 大连化物所生物技术部1823组 助理研究员
2022至今 大连化物所生物技术部1823组 副研究员
研究方向:酵母细胞工厂的构建以及甲醇生物转化研究
电话:0411-88133490
电子邮箱:jqgao@dicp.ac.cn
代表文章
1. Li J.J., Gao J.Q., Ye M., Cai P., Yu W., Zhai X.X., Zhou Y.J.*, Engineering yeast for high-level production of β-farnesene from sole methanol, Metab. Eng., 2024, 85, 194-200.
2. Xie L.F., Yu W., Gao J.Q., Wang H.Y., Zhou Y.J.*, Ogataea polymorpha as a next-generation chassis for industrial biotechnology, Trends Biotechnol., 2024, (In Press)
3. Xie L.F., Gao J.Q., Zhou Y.J.*, Synthetic biology for Taxol biosynthesis and sustainable production, Trends Biotechnol., 2024, 42(6), 674-676.
4. Gao J.Q.#., Yu W.#, Li Y.X., Jin M.J., Yao L., Zhou Y.J.*, Engineering co-utilization of glucose and xylose for chemical overproduction from lignocellulose, Nat. Chem. Biol., 2023, 19, 1524-1531. (Cover story)
5. Gao J.Q., Li Y.X., Yu W., Zhou Y.J.*, Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol, Nat. Metab., 2022, 4, 932-943.
6. Chen R.B., Gao J.Q., Yu W., Chen X.H., Zhai X.X., Chen Y., Zhang L.*, Zhou Y.J.*, Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast, Nat. Chem. Biol., 2022, 18, 520-529.
7. Yan C.X., Yu W., Yao L., Guo X.Y., Zhou Y.J., Gao J.Q.*, Expanding the promoter toolbox for metabolic engineering of methylotrophic yeasts,Appl. Microbiol. Biotechnol., 2022, 106(9-10), 3449-3464.
8. Yan C.X., Yu W., Zhai X.X., Yao L., Guo X.Y.*, Gao J.Q.*, Zhou Y.J., Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha, Synth. Syst. Biotechnol., 2022, 7, 498-505.
9. Li Y.X., Zhai X.X., Yu W., Feng D., Shah A.A., Gao J.Q.*, Zhou Y.J.*, Production of free fatty acids from various carbon sources by Ogataea polymorpha, Bioresour. Bioprocess., 2022, 9, 78.
10. 纪璐璐, 马小军, 高教琪*, 周雍进, 多形汉逊酵母启动子挖掘, 生物加工过程, 2022, 20(1), 20-28.
11. Gao J.Q., Gao N., Zhai X.X., Zhou Y.J.*, Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha, iScience, 2021, 24(3), 10216
12. 刘爽, 高教琪*, 薛闯, 周雍进, 多形汉逊酵母提高生长性能的培养基优化, 生物加工过程, 2020, 18, 116-125.
13. 高教琪, 周雍进*, 甲醇生物转化的机遇与挑战, 合成生物学, 2020, 1(2), 158-173.
专利
1. 周雍进, 高教琪, 高宁, 多形汉逊酵母基因编辑系统、其应用以及基因编辑方法, 专利号: CN202010628649.3
2. 周雍进, 高教琪, 李云霞, 一种重组多形汉逊酵母的构建方法及其应用, 专利号: CN202010626783.X
3. 周雍进, 高教琪, 李云霞,能够以甲醇为唯一碳源产脂肪酸工程菌的构建方法及其应用,专利号:202210044897.2