研究成果

期刊

书籍

专利

2021-

97. Yang S., Chen R.B., Cao X., Wang G.D., Zhou Y.J.*, De novo biosynthesis of the hops bioactive flavonoid xanthohumol in yeast, Nat. Commun., 2024, 15, 253.

96. Xie L.F., Yu W., Gao J.Q., Wang H.Y., Zhou Y.J.*, Ogataea polymorpha as a next-generation chassis for industrial biotechnology, Trends Biotechnol., 2024, (In Press)

95. Xie L.F., Gao J.Q., Zhou Y.J.*, Synthetic biology for Taxol biosynthesis and sustainable production, Trends Biotechnol., 2024, (In Press)

94. Ye M., Gao J.Q., Li J.J., Yu W., Bai F., Zhou Y.J.*, Promoter engineering enables precise metabolic regulation towards efficient β-elemene production in Ogataea polymorpha, Synth. Syst. Biotechnol., 2024, 9, 234-241.

93. Gao J.Q.#, Yu W.#, Li Y.X., Jin M.J., Yao L., Zhou Y.J.*, Engineering co-utilization of glucose and xylose for chemical overproduction from lignocellulose, Nat. Chem. Biol., 2023, 19, 1524-1531. (Cover story)

92. Zhai X.X., Gao J.Q., Li Y.X., Grininger M., Zhou Y.J.*,  Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast, Proc. Natl. Acad. Sci. USA, 2023, 120(12), e2220816120.

91. Cao C.Y., Zhang H.Y., Cao X., Kong S.J., Zhu B.W., Lin X.P*., Zhou Y.J.*, Construction and optimization of nonclassical Isoprenoid biosynthetic pathways in yeast peroxisomes for (+)-valencene production, 2023, J. Agric. Food Chem., 2023, 71, 11124-11130.

90. Wu X.Y., Cai P., Yao L., Zhou Y.J.*, Genetic tools for metabolic engineering of Pichia pastoris, Eng. Microbiol., 2023, 3, 100094.

89. Qiao S.J., Bai F., Cai P., Zhou Y.J., Yao L.*, An improved CRISPRi system in Pichia pastoris, Synth. Syst. Biotechnol., 2023, 8, 479-485.

88. Wu X.Y., Cai P., Gao L.H., Li Y.X., Yao L., Zhou Y.J.*,  Efficient bioproduction of 3‑hydroxypropionic acid from methanol by a synthetic yeast cell factory, ACS Sustainable Chem. Eng., 2023, 11, 6445-6453.

87. Ye M., Gao J.Q., Zhou Y.J.*, Global metabolic rewiring of the nonconventional yeast Ogataea polymorpha for biosynthesis of the sesquiterpenoid β-elemene, Metab. Eng., 2023, 76, 225-231.

86. Cao X., Yu W., Chen Y., Yang S., Zhao Z.K., Nielsen J., Luan H.W., Zhou Y.J.*, Engineering yeast for high-level production of diterpenoid sclareol, Metab. Eng., 2023, 75, 19-28.

85. Yu W., Gao J.Q., Yao L., Zhou Y.J.*, Bioconversion of methanol to 3‐hydroxypropionate by engineering Ogataea polymorpha, Chinese J. Catal., 2023, 46, 84-90.

84. Yan C.X., Gao N., Cao X., Yao L., Zhou Y.J., Gao J.Q.*, Auxotrophs compromise cell growth and fatty acid production in Saccharomyces cerevisiae, Biotechnol. J., 2023, 18(4), e2200510.

83. Cao C.Y., Gao J.Q., Zhu B.W., Zhou Y.J.*, Engineering yeast for bio‑production of food ingredients, Syst. Microbiol. Biomanuf., 2023, 3, 2-11.

82. 姚伦, 周雍进*, 一碳化合物生物利用和转化研究进展, 化工进展, 2023, 42(1), 16-29.

81. Gao J.Q., Li Y.X., Yu W., Zhou Y.J.*, Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol, Nat. Metab., 2022, 4, 932-943.

80. Cai P., Wu X.Y., Deng J., Gao L.H., Shen Y.W., Yao L., Zhou Y.J.*, Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris, Proc. Natl. Acad. Sci. USA, 2022, 119(29), e2201711119.

79. Chen R.B., Gao J.Q., Yu W., Chen X.H., Zhai X.X., Chen Y., Zhang L.*, Zhou Y.J.*, Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast, Nat. Chem. Biol., 2022, 18, 520-529.

78. Gao N.#, Gao J.Q.#, Yu W., Kong S.J., Zhou Y.J.*, Spatial-temporal regulation of fatty alcohol biosynthesis in yeast, Biotechnol. Biofuels Bioprod., 2022, 15, 141.

77. Zhai X.X., Yao L., Zhou Y.J., Construction of microbial chassis for terpenoid discovery, Synth. Syst. Biotechnol., 2022, 7, 1181-1182.

76. Kong S.J., Yu W., Gao N., Zhai X.X., Zhou Y.J.*, Expanding the neutral sites for integrated gene expression in Saccharomyces cerevisiae, FEMS Microbiol. Lett., 2022, 369, 1-5.

75. Zhang K., Duan X.P., Cai P.,Gao L.H., Wu X.Y., Yao L., Zhou Y.J.*, Fusing an exonuclease with Cas9 enhances homologous recombination in Pichia pastoris, Microb. Cell Fact., 2022, 21, 182.

74. Li Y.X., Zhai X.X., Yu W., Feng D., Shah A.A., Gao J.Q.*, Zhou Y.J.*, Production of free fatty acids from various carbon sources by Ogataea polymorpha, Bioresour. Bioprocess., 2022, 9, 78.

73. Yu W., Cao X., Gao J.Q., Zhou Y.J.*, Overproduction of 3-hydroxypropionate in a super yeast chassis, Bioresource Technol., 2022, 361, 127690.

72. Cai P., Li Y.X., Zhai X.X., Yao L., Ma X.J., Jia L.Y., Zhou Y.J.*, Microbial synthesis of long‑chain α‑alkenes from methanol by engineering Pichia pastoris, Bioresour. Bioprocess., 2022, 9, 58. (Featured article)

71. Cao C.Y., Cao X., Yu W., Chen Y.X., Lin X.P., Zhu B.W.*, Zhou Y.J.*, Global metabolic rewiring of yeast enables overproduction of sesquiterpene (+)-valencene, J. Agric. Food Chem., 2022, 70(23), 7180-7187.

70. Yan C.X., Yu W., Yao L., Guo X.Y., Zhou Y.J., Gao J.Q.*, Expanding the promoter toolbox for metabolic engineering of methylotrophic yeasts,Appl. Microbiol. Biotechnol., 2022, 106(9-10), 3449-3464.

69. Yan C.X., Yu W., Zhai X.X., Yao L., Guo X.Y.*, Gao J.Q.*, Zhou Y.J., Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha, Synth. Syst. Biotechnol., 2022, 7, 498-505.

68. Ji D.W., Hu Y.C., Min X.T., Liu H., Zhang W.S., Li Y., Zhou Y.J., Chen Q.A.*, Skeleton-Reorganizing coupling reactions of cycloheptatriene and cycloalkenones with amines, Angew. Chem. Int. Ed. Engl., 2022, e202213074.

67. Hou R., Gao L.H., Liu J.H., Liang Z., Zhou Y.J.*, Zhang L.H.*, Zhang Y.K., Comparative proteomics analysis of Pichia pastoris cultivating in glucose and methanol, Synth. Syst. Biotechnol., 2022, 7, 862-868.

66. 纪璐璐, 马小军, 高教琪*, 周雍进, 多形汉逊酵母启动子挖掘, 生物加工过程, 2022, 20(1), 20-28.

65. 冯叨, 高教琪, 龚志伟*, 周雍进*, 多形汉逊酵母代谢改造生产脂肪酸及发酵条件优化, 生物工程学报, 2022, 38(2), 760-771.

64. Cai P.#, Duan X.P.#, Wu X.Y., Gao L.H., Ye M., Zhou Y.J.*, Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia Pastoris, Nucleic Acids Res., 2021, 49(13), 7791-7805.

63. Gao J.Q., Gao N., Zhai X.X., Zhou Y.J.*, Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha, iScience, 2021, 24(3), 102168.

62. Yu W., Gao J.Q., Zhai X.X., Zhou Y.J.*, Screening neutral sites for metabolic engineering of methylotrophic yeast Ogataea polymorpha, Synth. Syst. Biotechnol., 2021, 6, 63-68.

61. Zhai X.X., Ji L.L., Gao J.Q., Zhou Y.J.*, Characterizing methanol metabolism‑related promoters for metabolic engineering of Ogataea polymorpha, Appl. Microbiol. Biotechnol., 2021, 105, 8761-8769.

60. 叶敏, 高教琪, 周雍进*, 非常规酵母细胞工厂合成天然产物, 生物技术通报, 2021, 37(8): 12-24.

59. 高琳惠, 蔡鹏, 周雍进*, 甲醇酵母代谢工程研究进展, 生物工程学报, 2021, 37(3), 966-979.