课题组成员

蔡鹏     博士后

个人简历

2007-2011 南京林业大学 学士学位

2011-2014 南京林业大学 硕士学位

2014-2017上海交通大学 博士研究生

2017-2018 浙江大学 化学工程与生物工程学院 科研助理

2018-2022 大连化学物理研究所与大连理工大学 联合培养 博士学位

2022至今   大连化物所生物技术部1823组 博士后

研究方向:甲醇的高效生物转化及酵母合成生物学方法的开发

电话:0411-88133490

电子邮箱:jasoncai@dicp.ac.cn

代表文章

1. Gao L.H.#, Hou R.#, Cai P., Yao L., Wu X.Y., Li Y.X., Zhang L.H.*, Zhou Y.J.*, Engineering Yeast Peroxisomes for α-Bisabolene Production from Sole Methanol with the Aid of Proteomic Analysis, JACS Au, 2024, 2474-2483.

2. Shen Y.W., Cai P., Gao L.H., Wu X.Y., Yao L., Zhou Y.J.*, Engineering high production of fatty alcohols from methanol by constructing coordinated dual biosynthetic pathways, Bioresour. Technol., 2024, 412, 131396.

3. Gao L.H., Zhang K., Shen Y.W., Cai P.*, Zhou Y.J.*, Engineering a versatile yeast platform for sesquiterpene production from glucose or methanol, Biotechnol. J., 2024, 19, 2400261.

4. Wu X.Y., Cai P., Yao L., Zhou Y.J.*, Genetic tools for metabolic engineering of Pichia pastoris, Eng. Microbiol., 2023, 3, 100094.

5. Qiao S.J., Bai F., Cai P., Zhou Y.J., Yao L.*, An improved CRISPRi system in Pichia pastoris, Synth. Syst. Biotechnol., 2023, 8, 479-485.

6. Wu X.Y., Cai P., Gao L.H., Li Y.X., Yao L., Zhou Y.J.*,  Efficient bioproduction of 3‑hydroxypropionic acid from methanol by a synthetic yeast cell factory, ACS Sustainable Chem. Eng., 2023, 11, 6445-6453.

7. Cai P., Wu X.Y., Deng J., Gao L.H., Shen Y.W., Yao L., Zhou Y.J.*, Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris, Proc. Natl. Acad. Sci. USA, 2022, 119(29), e2201711119.

8. Cai P., Li Y.X., Zhai X.X., Yao L., Ma X.J., Jia L.Y., Zhou Y.J.*, Microbial synthesis of long‑chain α‑alkenes from methanol by engineering Pichia pastoris, Bioresour. Bioprocess., 2022, 9, 58. (Featured article)

9. Zhang K., Duan X.P., Cai P.Gao L.H., Wu X.Y., Yao L., Zhou Y.J.*, Fusing an exonuclease with Cas9 enhances homologous recombination in Pichia pastoris, Microb. Cell Fact., 2022, 21, 182.

10. Cai P.#, Duan X.P.#, Wu X.Y., Gao L.H., Ye M., Zhou Y.J.*, Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia Pastoris, Nucleic Acids Res., 2021, 49(13), 7791-7805.

11. Cai P., Gao J.Q., Zhou Y.J.*, CRISPR-mediated genome editing in non-conventional yeasts for biotechnological applications, Microb. Cell Fact., 2019, 18, 63.